Analysis and Experimental Design

Is a poor analytical technique preventing you from moving forward with your chemistry? We often see cases where the analysis of a reaction intermediate is highly problematic and implies inconsistent results, when it is in fact the analytical method which is giving rise to the problems.

Improve Your Process with Design of Experiments

Do you ever find yourself wishing you could understand more about the system you are working with, but are told you don’t have the time to do additional reactions?

What design to use and when

Case Study 8

A case study showing how advanced DoE with PCA can be used at the start of a process to efficiently screen a large number of variables. In this case, PCA was applied to identify the catalyst, ligand and solvent requirements for a new catalytic reaction.

Case Study 7

A cautionary tale about factor selection. The identification of significant factors is the difference between success and failure of a design. When a tried and tested experiment failed a user trial before the start of a new campaign, experimental design was used to uncover the problem.

Factor Selection: completed fishbone and tips

Factor Selection for a Screening Experiment

Where can DoE fit in process development?

Are you using DoE to its full potential?

What is experimental design?

The first post in the DoE demystified series introducing experimental design

DoE Demystified

A series of posts going back to the basics of experimental design